منابع مشابه
Osteopathic medical education in 2009: sails set for improved healthcare?
Shannon • Editorial O medical education (OME) is constantly changing to meet the evolving needs of the profession and the nation’s healthcare system in which it exists. Although the benefits of some recent modifications have been debated,1-3 the growth of the profession is undeniable, as evidenced in the contributions4-9 to this year’s OME theme issue of JAOA—The Journal o f the American Osteop...
متن کاملATP turnover by individual myosin molecules hints at two conformers of the myosin active site.
Coupling of ATP hydrolysis to structural changes in the motor domain is fundamental to the driving of motile functions by myosins. Current understanding of this chemomechanical coupling is primarily based on ensemble average measurements in solution and muscle fibers. Although important, the averaging could potentially mask essential details of the chemomechanical coupling, particularly for mix...
متن کاملThe active site of myosin adenosine triphosphatase. I. Localization of one of the sulfhydryl groups.
It is now widely recognized that under certain conditions of temperature and pH (1, 2)) the Ca++-activated hydrolysis of adenosine triphosphate (ATP) by myosin exhibits a biphasic response to titration of the sulfhydryl groups of the protein by organic mercurials and by N-ethylmaleimide (3-5). On the other hand, titration by these reagents results only in inhibition if inosine triphosphate or g...
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ژورنال
عنوان ژورنال: Nature
سال: 1980
ISSN: 0028-0836,1476-4687
DOI: 10.1038/283621a0